분양항목 안내
| 대분류 | 소분류 | 분류내역 |
|---|---|---|
| 1차 자원 | 인체유래물 | 1. 혈장(150ul/vial) 2. 혈청(150ul/vial) 3. DNA(500ng/ul) 4. 환자유래 섬유아세포 (1X106cell/ml) 5. 환자유래 PBMC (1X106cell/ml) |
| 임상/역학정보 | 1. 접수정보 2. 환자정보 3. 신체계측 4. 질병력 5. 질환가족력 6. 음주흡연 7. 임상검사 8. 신경심리평가 9. 진단 10. 유전정보(ApoE genotyping) 11. 영상검사 | |
| 유전정보 | 1. K-chip (800,000 SNP array for S.Korean) | |
| 뇌영상 | 1. 뇌영상 MRI raw files (dicom/nifti) 2. Amyloid PET raw files (dicom/nifti) | |
| 라이프로그 | 1. 라이프로그 preprocessed files (actigraphy) | |
| 심층 자료/ 2차자원 |
인체유래물 (혈액 & 세포) |
1. Plasma SIMOA (t-tau, amyloid-beta 40, 42) 2. Plasma Proteomics (OLINK & SomaScan platform) 3. Fibroblast circadian rhythm parameters(cellular period by ex-vivo experiments) |
| 뇌영상 |
1. Amyloid PET: Cortical, and subcortical regional centiloid (for analysis and multi-data integration) 2. sMRI: Voxel-based Morphology Parameters (166 brain area grey matter density by AAL1, AAL3) 3. fMRI: Functional connectivity map matrix (112 x 112 brain area connectivity matrix) 4. fMRI: Amplitude of low frequency fluctuations (reflecting spontaneous brain activity) 5. MRI-DTI: FA, MD, AD parameters (white matter integrity parameters) |
|
| 라이프로그 |
1. Actigraphy parameters (mean activity based basic parameters, physical activity behavioral circadian rhythm parameters, rest-activity pattern transition parameters) |
|
| 유전체 |
1. Polygenic Risk Scores (3 parameters for vascular dementia, Alzheimer’s disease, and clinical dementia |